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Most Statin Side Effects Are Not Caused by the Drug, Major Review Finds

Rubenhair Latvia
2 min read
08.02.2026
Most Statin Side Effects Are Not Caused by the Drug, Major Review Finds

A recent review has found that most reported side effects of statin medications are not supported by scientific evidence. The study, published in The Lancet, analyzed 66 potential side effects and found only four to be linked to statin use.

A recent review has found that most reported side effects of statin medications are not supported by scientific evidence.

The study, published in The Lancet, analyzed 66 potential side effects and found only four to be linked to statin use. This suggests that many of the concerns about statins may be unfounded.

Despite their widespread use, statins remain a safe and effective treatment for high cholesterol (hyperlipidemia). In fact, an estimated 200 million adults worldwide take statins to manage their cholesterol levels.

The study's findings are reassuring for individuals who have concerns about taking statins. Rigved Tadwalkar, MD, consultative cardiologist and director of Digital Transformation Pacific Heart Institute in Santa Monica, CA, notes that the benefits of statins outweigh the risks for appropriately selected patients.

What does this mean for you?

When reading about potential side effects on medication labels, it's essential to understand that not all listed side effects are supported by strong evidence. In fact, many may be unrelated to the drug itself.

Donald Lloyd-Jones, MD, past president of the American Heart Association (AHA), explains that any adverse reactions reported during a study must be listed on the label, including common events like colds or accidents. However, this does not necessarily mean that these events were caused by the medication.

This study provides clarity and reassurance for individuals taking statins. If you have concerns about your medication or treatment plan, we encourage you to discuss them with our healthcare team.

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