on PinterestOzempic is now available as a reformulated oral tablet for people with type 2 diabetes.
on PinterestOzempic is now available as a reformulated oral tablet for people with type 2 diabetes. Image courtesy of Novo Nordisk
- The GLP-1 medication Ozempic is now available in pill form for people with type 2 diabetes.
- The oral tablet is a reformulated version of the current Rybelsus pill but comes in smaller doses.
- Experts say the pill may be a better alternative for people who don’t want to administer weekly injections of Ozempic.
A pill form of the widely prescribed GLP-1 medication Ozempic is now available in the United States.
Officials at Novo Nordisk have announced that an oral tablet version of the GLP-1 drug became available on May 4 for adults diagnosed with type 2 diabetes.
The Ozempic pill is replacing Novo Nordisk’s Rybelsus daily oral medication, which was approved in 2019 for type 2 diabetes by the Food and Drug Administration (FDA) in 3 milligram (mg), 7 mg, and 14 mg doses.
The Ozempic daily pill is a reformulation of Rybelsus and comes in 1.5 mg, 4 mg, and 9 mg doses.
Novo Nordisk officials say the new formulation delivers the same efficacy and safety profile as the originally approved formulation, but at a lower dose.
Ozempic will also remain available as a weekly injection for diabetes treatment. It is also commonly prescribed off-label for weight loss.
This is the third GLP-1 medication to be approved in pill form this year. In January, FDA regulators gave the OK for another Novo Nordisk product, Wegovy, to be sold as an oral tablet. Wegovy is approved for use for weight management.
In April, the FDA also approved the Eli Lilly medication Foundayo in pill form, but the agency ordered the company to study the heart, liver, and other potential risks associated with this new pill. Foundayo has been approved for use in weight management.
Novo Nordisk officials say they expect a decision from federal regulators on a 25-mg Ozempic tablet dose by the end of 2026. They add that the new pill provides more options for patients.
“With an updated formulation and new branding, oral semaglutide, now under the Ozempic name, helps patients and healthcare professionals more easily recognize the available FDA-approved treatment options for type 2 diabetes that contain the semaglutide molecule,” said Michael Radin, MD, the executive medical director for Novo Nordisk.
“By offering Ozempic in both a pill and injection form, patients can work with their healthcare professional to pick the option that best fits their lives and daily routines,” Radin told Healthline.
Pouya Shafipour, MD, a family and obesity medicine physician at Providence Saint John’s Health Center in Santa Monica, CA, said a pill form of Ozempic will likely be more appealing to many people than an injection.
“A lot of people are needle-averse,” Shafipour told Healthine. “Over the long term, a lot of people get tired of poking themselves.”
Mir Ali, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, said the significance of the new Ozempic-branded pill is that it “carries greater name recognition.”
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